0 avis
Water-Soluble Ruthenium (II) Complex Derived From Optically Pure Limonene and Its Microencapsulation Are Efficient Tools Against Bacterial Food Pathogen Biofilms: Escherichia coli, Staphylococcus aureus, Enteroccocus faecalis, and Listeria monocytogenes
Archive ouverte : Article de revue
Edité par HAL CCSD ; Frontiers Media
International audience. Bioactive aminooxime ligands based on optically pure (R)-limonene have been synthesized in two steps. Their ruthenium (II) cationic water-soluble complex was prepared by a reaction between dichloro (para-cymene) ruthenium (II) dimers and aminooxime ligands in a 1:2 molar ratio. Antibacterial and antibiofilm activities of the synthetized complex were assessed against Escherichia coli , Staphylococcus aureus , Listeria monocytogenes , and Enterococcus faecalis. The results revealed that the ruthenium (II) complex has higher antibacterial and antibiofilm activities in comparison with free ligands or the enantiopure (R)-limonene. Moreover, microencapsulation of this complex reduced its cytotoxicity and improved their minimum inhibitory concentration and antibiofilm activity toward the considered bacteria. The ruthenium (II) complex targets the bacterial cell membrane, which leads to rapid leakage of intracellular potassium. Our study suggests that the developed ruthenium (II) complexes could be useful as an alternative to conventional disinfectants.
Consulter en ligne
Suggestions
Du même auteur
Du même sujet
![Le séminaire de Jacques Lacan. [Livre IV], [La relation d'objet] : [1956-1957] / Jacques Lacan | Lacan, Jacques (1901-1981). Auteur](https://covers.syracuse.cloud/Cover/ICTL/MONO/8Gu3Cbv2hW7Fgqa8yQYaGg2/9782020147224/MEDIUM?fallback=https%3a%2f%2fbibliotheque.univ-catholille.fr%2fui%2fskins%2fICTL%2fportal%2ffront%2fimages%2fGeneral%2fDocType%2fMONO_MEDIUM.png "Plus d'infos sur 'Le séminaire de Jacques Lacan. [Livre IV], [La relation d'objet] : [1956-1957] / Jacques Lacan'")
![Le séminaire de Jacques Lacan. [Livre V], [Les formations de l'inconscient] : [1957-1958] / Jacques Lacan | Lacan, Jacques (1901-1981). Auteur](https://covers.syracuse.cloud/Cover/ICTL/MONO/Hmr70N2yD7K-yU-AeLcwSA2/9782020256681/MEDIUM?fallback=https%3a%2f%2fbibliotheque.univ-catholille.fr%2fui%2fskins%2fICTL%2fportal%2ffront%2fimages%2fGeneral%2fDocType%2fMONO_MEDIUM.png "Plus d'infos sur 'Le séminaire de Jacques Lacan. [Livre V], [Les formations de l'inconscient] : [1957-1958] / Jacques Lacan'")
![Amour et crises dans la famille recomposée : [les enjeux psychiques de la recomposition familiale] / Catherine Audibert | Audibert, Catherine. Auteur](https://covers.syracuse.cloud/Cover/ICTL/MONO/175gnOK1dVvsrPyXYvtqCw2/9782228924702/MEDIUM?fallback=https%3a%2f%2fbibliotheque.univ-catholille.fr%2fui%2fskins%2fICTL%2fportal%2ffront%2fimages%2fGeneral%2fDocType%2fMONO_MEDIUM.png "Plus d'infos sur 'Amour et crises dans la famille recomposée : [les enjeux psychiques de la recomposition familiale] / Catherine Audibert'")
