Glioblastoma migration along constraints with different geometries: how to mimick brain parenchyma invasion? | Tarhan, Mehmet
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Glioblastoma migration along constraints with different geometries: how to mimick brain parenchyma invasion?

Archive ouverte : Communication dans un congrès

Tarhan, Mehmet | Mutel, Alexandre | Desrues, Laurence | Collard, Dominique | Castel, Hélène

Edité par HAL CCSD

International audience. A microfluidic device is demonstrated to analyze glioblastoma migration along constraints with precisely designed geometries. This in-vitro model reveals physiologically relevant glioma invasion scenarios: full migration along constraints, suspended motion by extreme constriction, and limited migration associated with the ejection of plasma membrane particles due to the continuing extension.

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