Influence of common preanalytical variations on the metabolic profile of serum samples in biobanks | Fliniaux, Ophelie
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Influence of common preanalytical variations on the metabolic profile of serum samples in biobanks

Archive ouverte : Article de revue

Fliniaux, Ophelie | Gaillard, Gwenaelle | Lion, Antoine | Cailleu, Dominique | Mesnard, François | Betsou, Fotini

Edité par HAL CCSD ; Springer Verlag

International audience. A blood pre-centrifugation delay of 24 h at room temperature influenced the proton NMR spectroscopic profiles of human serum. A blood pre-centrifugation delay of 24 h at 4°C did not influence the spectroscopic profile as compared with 4 h delays at either room temperature or 4°C. Five or ten serum freeze-thaw cycles also influenced the proton NMR spectroscopic profiles. Certain common in vitro preanalytical variations occurring in biobanks may impact the metabolic profile of human serum.

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