Optimization of surface treatment on MEMS probes for single-cell capture and release

Archive ouverte : Article de revue

Hayashi, Kensaku | Kumemura, Momoko | Kaneda, Shohei | Menon, Vivek | Jalabert, Laurent | Tachikawa, Saeko | Tarhan, Mehmet | Fujii, Teruo | Kim, Beomjoon | Fujita, Hiroyuki

Edité par HAL CCSD ; Myu scientific publishing

International audience. Micro-electromechanical systems (MEMS) tweezers developed for the trapping and characterization of bio molecules such as DNA are also capable of cell handling, which will enable further application involving single cell characterization. However, cellular adhesion to Si tweezers surfaces can inhibit the release of cells after capture and analysis. To allow for high-throughput cell handling, the surface modification process for probe sidewalls was optimized. The hydrophilicity of sample silicon wafers modified with various chemical coatings was measured to identify the optimal process. The surface modification was then applied to MEMS probes and the feasibility of cell capture/release was evaluated.

Consulter en ligne

Suggestions

Du même auteur

Fabricating Silicon Resonators for Analysing Biological Samples. Fabricating Silicon Resonators for Analysing Biological Samples: [Review] | Kumemura, Momoko

Fabricating Silicon Resonators for Analysing Biological Samples. Fabricatin...

Archive ouverte: Article de revue

Kumemura, Momoko | 2021-12-12

International audience. The adaptability of microscale devices allows microtechnologies to be used for a wide range of applications. Biology and medicine are among those fields that, in recent decades, have applied ...

Size and Flexibility Define the Inhibition of the H3N2 Influenza Endonuclease Enzyme by Calix[n]arenes | Tauran, Yannick

Size and Flexibility Define the Inhibition of the H3N2 Influenza Endonuclea...

Archive ouverte: Article de revue

Tauran, Yannick | 2019-06

International audience. Inhibition of H3N2 influenza PA endonuclease activity by a panel of anionic calix[n]arenes and β-cyclodextrin sulfate has been studied. The joint experimental and theoretical results reveal t...

Les protestantismes en Lorraine, XVIe-XXIe siècle / Laurent Jalabert, Julien Léonard, dir. | Jalabert, Laurent (1967-....) - historien. Directeur de publication

Les protestantismes en Lorraine, XVIe-XXIe siècle / Laurent Jalabert, Julie...

Livre | Jalabert, Laurent (1967-....) - historien. Directeur de publication | 2019

Du même sujet

Influence of different surface treatments on the water absorption capacity of flax fibres Rheology of fresh reinforced-mortars and mechanical properties in the hardened state | Page, J.

Influence of different surface treatments on the water absorption capacity ...

Archive ouverte: Article de revue

Page, J. | 2019

International audience. An experimental investigation was undertaken on the influence of different surface treatments of flax fibres on mortar properties in both fresh and hardened states. Three types of coating wer...

Chargement des enrichissements...