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Investigation and modeling of Residence Time Distribution and thermal dissipation in a Dynamic Filtration module
Archive ouverte : Communication dans un congrès
Edité par HAL CCSD
In: 16ème Congrès de la Société Française de Génie des Procédés (SFGP), 11 - 13 July 2017, Nancy, France. Récents Progrès en Génie des Procédés, Numéro 110 – 2017 ISSN: 1775-335X ; ISBN: 978-2-910239-85-5, Ed. SFGP, Paris, France
In: 16ème Congrès de la Société Française de Génie des Procédés (SFGP), 11 - 13 July 2017, Nancy, France. Récents Progrès en Génie des Procédés, Numéro 110 – 2017 ISSN: 1775-335X ; ISBN: 978-2-910239-85-5, Ed. SFGP, Paris, France.
Bioprocess often associates bioreactor and membrane separation. Bioprocess performances are intrinsically related to the capacity to control and to maintain microbial cells to their optimal activity (integrity, viability and productivity) while industrial operating conditions generate stressful environment or at least no ideal conditions. In present case, high shear rates and Joule effects are generated within a specific dynamic filtration module. Then, Residence Time Distribution (RTD) in a module, named Rotating and Vibrating Filtration (RVF), in which a three-blade impeller rotates between two membranes, was studied in laminar (Remixing<1×103) and turbulent (Remixing>3×104) regimes. In addition, thermal effects of mixing rate under several flow rates and regimes were reported. The magnitude and duration of stressful conditions stand as critical parameters which were quantified and modeled to engineer and to design intensive bioprocess.
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